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Eptifibatide

Product Item : CAS 188627-80-7
Category： peptides
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Product description：Eptifibatide is a synthetic cyclic heptapeptide antiplatelet agent, derived from the disintegrin peptide of southeastern pygmy rattlesnake venom. It acts as a **reversible, selective glycoprotein IIb/
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Eptifibatide is a synthetic cyclic heptapeptide antiplatelet agent, derived from the disintegrin peptide of southeastern pygmy rattlesnake venom. It acts as a reversible, selective glycoprotein IIb/IIIa (GP IIb/IIIa) receptor antagonist on human platelets.

It blocks the final common pathway of platelet aggregation: it prevents fibrinogen, von Willebrand factor and other adhesive ligands from binding to GP IIb/IIIa receptors, thus inhibiting platelet cross-linking and thrombus formation. The antiplatelet effect is reversible; platelet function recovers rapidly after stopping infusion.

Clinically, it is administered intravenously for:

Acute coronary syndrome (unstable angina and non‑ST‑elevation myocardial infarction, NSTEMI)
Patients undergoing percutaneous coronary intervention (PCI), including coronary stenting, to reduce risk of myocardial infarction and urgent revascularization.

It is commonly used in combination with aspirin and heparin.

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