Glp-1 receptor activation: Inhibits appetite, delays gastric emptying; Glucose-dependent insulin secretion is promoted to lower blood sugar and HbA1c.
2. GIP (glucose-dependent insulin-stimulating polypeptide) receptor activation: Enhances the weight loss effect of GLP-1, further inhibits food intake, and protects β -cell function.
3. GCGR (glucagon receptor) activation: Enhances energy expenditure, promotes fat breakdown, and reduces visceral fat; Improve fat accumulation in the liver.
In a nutshell: reducing intake, enhancing satiety, and increasing energy expenditure - the intensity of weight loss is currently among the top tier of peptide drugs