Mechanism of action
Intermittent administration daily selectively activates PTH1R on the surface of osteoblasts, prioritizing the stimulation of osteoblast activity to promote new bone formation (simultaneous increase in trabecular bone and cortical bone); The stimulation of osteoclast bone resorption is weaker than that of teriparatide, and the risk of hypercalcemia is lower.
Core features: Promoting bone formation > bone resorption, net increase in bone density and enhancement of bone strength